Tylenol is a popular North American brand of drugs for relieving pain, reducing fever, and relieving the symptoms of allergies, cold, cough, and flu. The active ingredient of its original, flagship product, acetaminophen (called "paracetamol" outside of North America), is marketed for headaches, fever, muscle and body pain, arthritis, and joint pain. Like the words "acetaminophen" and "paracetamol", the brand name is derived from the chemical name for the compound, N-acetyl-para-aminophenol (APAP). It is available over the counter without prescription, has few side effects, and reacts with very few medications. However, it can have fatal interactions with large amounts of alcohol. In addition to products related to allergies and cold, Johnson & Johnson also sells a stronger pain reliever containing codeine.

What is Tylenol?
Tylenol is a pain reliever and a fever reducer. It works by lowering a chemical in the brain that stimulates pain nerves and the heat-regulating center in the brain.

Tylenol is used to treat many conditions such as headache, muscle aches, arthritis, backache, toothaches, colds, and fevers.

Tylenol may also be used for purposes other than those listed in this medication guide.

Tylenol is currently the most popular painkiller in the United States. Americans take over 8 billion pills (tablets or capsules) of Tylenol each year. Acetaminophen is the general (generic) name for Tylenol, which is a brand name. Although acetaminophen is contained in over 200 medications, most of them do not have the name "Tylenol" on their labels. Moreover, just about every patient with liver disease in my practice invariably asks: "Is it safe for me to take Tylenol?" or "How much Tylenol can I take?" These questions highlight the public`s awareness of the potential for acetaminophen to cause liver damage or injury.

Tylenol is a very effective pain-killing (analgesic) and fever-reducing (anti-pyretic) agent. It is also a very safe drug as long as the recommended dosage is not exceeded. In fact, the use of Tylenol instead of aspirin to treat fevers in infants has greatly reduced the occurrence of Reye`s syndrome, an often fatal form of liver failure. Ironically, however, taking too much Tylenol (an overdose) can also cause liver failure, although by a different process (mechanism), as discussed below.

Important information about Tylenol
Use Tylenol for up to 3 days for fever or up to 10 days for pain (or up to 5 days to treat a child`s pain). If the symptoms do not improve, or if they get worse, stop using Tylenol and see a doctor.
Avoid alcohol during treatment with Tylenol. Taken together they can be damaging to the liver.

Be aware of the Tylenol content of other over-the-counter and prescription products. Care should be taken to avoid taking more than the recommended amount of acetaminophen per dose or per day.

Before taking Tylenol
Do not take Tylenol without first talking to your doctor if you drink more than three alcoholic beverages per day or if you have had alcoholic liver disease. You may not be able to take Tylenol, or you may require a lower dose or special monitoring. Before taking this medication, tell your doctor if you have kidney or liver disease. You may not be able to take Tylenol, or you may require a dosage adjustment or special monitoring during treatment if you have either of these conditions. Tylenol has not been formally assigned to a pregnancy category by the FDA. It is routinely used for short term pain relief and fever in all stages of pregnancy. This medication is believed to be safe in pregnancy when used intermittently for short durations. this medication should only be given during pregnancy when need has been clearly established. this medication passes into breast milk. It appears to be safe for use during breast-feeding but should be avoided if possible. Talk to your doctor before taking this medication if you are breast-feeding a baby. If you are treating a child, read the package carefully and use a pediatric form of the medication if possible. Talk to a doctor first if the child is younger than 2 years of age.

How should I take this medication?
Take Tylenol exactly as directed by your doctor or follow the instructions on the package. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each oral dose with a full glass of water.

Tylenol can be taken with or without food.
Wash your hands before and after using the rectal suppositories. Run the suppository under cold water or put it in the refrigerator for a few minutes before using it. Remove any wrapping from the suppository and moisten the suppository with cold water. Squat, stand, or lie down with one leg straight and the other bent, in a comfortable position that allows access to the rectal area. Use your finger, or the applicator if one is provided, to deposit the suppository as far as it will comfortably go into the rectum. Insert the narrow end first. Close your legs and lie still for a few minutes. If the applicator will be reused, take it apart and wash it with warm water and mild soap, then dry it completely. Avoid having a bowel movement for at least 1 hour after inserting the suppository. To ensure that you get a correct dose, measure the liquid forms of Tylenol with a special dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one. Shake the liquid well before measuring. Never take more Tylenol than is directed. The maximum amounts for adults are 1 gram (1000 mg) per dose and 4 grams (4000 mg) per day. Taking more Tylenol could be damaging to the liver. If you drink more than three alcoholic beverages per day, talk to your doctor before taking this medication.

Use Tylenol for up to 3 days for fever or up to 10 days for pain (or up to 5 days to treat a child`s pain). If the symptoms do not improve, or if they get worse, stop using this medication and see a doctor.
If you are treating a child, read the package carefully and use a pediatric form of the medication if possible. Talk to a doctor first if the child is younger than 2 years of age. Store this medication at room temperature away from heat, moisture, and the reach of children. The rectal suppositories can be stored at room temperature or in the refrigerator.


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